Roger Y. Tsien grows up in New Jersey and there he attends Livingston High School.

Roger Y. Tsien attends Harvard University and graduates summa cum laude in physics and chemistry.

Throughout Roger Y. Tiens's work on GFP (Green Fluorescent Protein), he successfully creates various GFP mutants and new variants of GFP that shine brighter and in different colours. Moreover he shows that it needs oxygen but no other proteins to form GFP chromophore in a chemical reaction.

In 2008 Roger Y. Tsien receives the Nobel Prize in Chemistry "for the discovery and development of the green fluorescent protein, GFP." He shares it with Osamu Shimomura and Martin Calfie.

Having received his bachelor's degree, Roger Y. Tsien moves to Churchill College, Cambridge. There he studies physiology and gains his PhD.

Because Roger Y. Tsien is looking for improved research conditions, he switches to the University of California, San Diego to work as a Professor for Pharmacology, Chemistry and Biochemistry. He also becomes investigator of the Howard Hughes Medical Institute. This new environment is where, due to him the 'highlights of the science' started.

Roger Y. Tsien marries Wendy Globe Tsien, whom he met at a Christmas fest in 1976.

Because of his studies on Ca2+ signaling, amongst others, Roger Y. Tsien is offered a Assistant Professorship at the Department of Physiology-Anatomy, University of California, Berkeley. He and his team synthesize improved Ca2+ and Na+ indicators.

After his PhD, Roger Y. Tsien stays at Harvard and becomes a postdoctoral Research Fellow at Gonville & Caius College. He focuses on Ca2+ signaling.

On 1st February 1952 Roger Y. Tsien is born as third child to his parents who immigrated from China to the U.S. five years before.

At the age of 16 Roger Y. Tsien wins the Westinghouse Science Talent Search and gains a National Merit Scholarship.