Osamu Shimomura becomes a Senior Scientist at the Marine Biological Laboratory (MBL). Because of that he and his wife Akemi, who works as Shimomura's research assistant, move to Massachusetts. There he continues studying the luminescent substance of several organisms.
Osamu Shimomura attends his first Lindau Meeting in 2009 which is dedicated to chemistry.
Osamu Shimomura visits Bermuda and studies the luciferin of the fireworm Odontosyllis enopla.
Noticing that he is not able to do top-level work in earth science and bioluminescence in Japan, Osamu Shimomura decides to return to Princeton University. He targets working on the chemical mechanism of aequorin bioluminescence. For more than ten years he, his wife and his team spend the summers at Friday Harbor (Washington) collecting jellyfish for their research.
After Osamu Shimomura retired from the Marine Biological Laboratory, he sets up a Photoprotein Laboratory at home in order to do more experiments.
At the top of his class, Osamu Shimomura graduates from Nagasaki Pharmacy School and gains a BSc in pharmacy.
Osamu Shimomura moves to Nagoya University and becomes research student of Professor Yoshimasa Hirata. There he advances and becomes successful in extracting, purifying and crystallizing the enzym Cypridina luceferin.
Osamu Shimomura and his team determine the structure of a part of the aequorin chromophore. It takes six more years until they get a general understanding of the aequorin luminescance reaction.
In summer 1970 Akemi Okubo, a graduate of the Pharmacy Department, and Osamu Shimomura get married.
Osamu Shimomura is born in the town of Fukuchiyama in Japan to his mother Yukie and his father Chikara.
Right after graduation from Nagasaki Pharmacy School, Osamu Shimomura decides to accept a job offer as an assistant in the analytical chemistry laboratory for students at the Department of Pharmacy, Nagasaki University.
Dr. Frank Johnson invites Osamu Shimomura working with him on the bioluminescence of the luminous jellyfish Aequorea at Princeton University.
Osamu Shimomura illuminates the chromophore of GFP (Green Fluorescent Protein).
Professor Hirata offers Osamu Shimomura a position as associate professor at the Water Science Institute (now Hydrospheric Atomspheric Research Center), where Shimomura works under Professor Tadashiro Koyama. There he and Yoshiti Kishi successfully purify and crystallize luciferin from frozen Cypridina. As a consequence they are able to identify the structure of luciferin (1965).
Within their work Osamu Shimomura and other scientists extract a luminescent protein that they name aequorin. In company with calcium ions aequorin emits light, even in the abscence of oxygen. It is the first photoprotein ever discovered.
Being invited to Princeton University, Osamu Shimomura's professor Hitara awards him a doctoral degree in organic chemistry for his work on Cypridina.
Without graduation ceremony and diploma Osamu Shimomura graduates in 1945 at the factory where he and other students are working during the years of war.
In 2008 Osamu Shimomura receives the Nobel Prize in Chemistry "for the discovery and development of the green fluorescent protein, GFP."