Robert Lefkowitz and Brian K. Kobilka are awarded the Nobel Prize in Chemistry in 2012 for their studies of G-protein-coupled receptors.

Robert Lefkowitz enters the Massachusetts General Hospital for an additional year of medical residency, followed by two years of cardiology. He joins Edgar Haber's laboratory and tries to prove the exsistence of β-adrenergic receptors.

After graduation Robert Lefkowitz remains at Columbia for two years of house staff training in internal medicine at the Columbia Presbyterian Medical Centre.

Robert Lefkowitz enters Columbia Medical School and focuses on clinical work. Paul Marks shows him how scientific information can be used to work on clinical problems. Among his classmates during this time is Harold Varmus. Lefkowitz graduates in 1966.

Robert Lefkowitz marries Arna Gornstein. They have five children.

Robert Lefkowitz marries Lynn Tilley of Durham.

Robert Lefkowitz enters The Bronx High School of Science where he becomes particularly interested in chemistry.

Robert Lefkowitz is apponited Associate Professor of Medicine and Assistant Professor of Biochemistry at Duke University Medical Center. In 1982 he is promoted to James B. Duke Professor of Medicine. Lefkowitz focuses on G protein coupled receptors and β-arrestin proteins. He achieves a number of research successes, including the isolation of the four then known adrenergic receptor subtypes, the discovery of constitutively active mutant receptors and the cloning of cDNAs which reveals the homology with rhodopsin.

Robert Lefkowitz attends Columbia Universtiy and enroles as a pre-medical student majoring in chemistry. He is influenced by Ronald Breslow among others, who introduces him to biochemistry.

Robert Lefkowitz does not want to be drafted into the army and joins the United States Public Health Service to work clinical and in the laboratory in 1968. He works under Jesse Roth and Ira Pastan in the Clinical Endocrinology Branch and supervises an in-patient service. He develops a radioligand binding method to study the putantive receptors for adrenocorticotropic hormone. The success makes him consider a career in research.

Robert Joseph Lefkowitz is born in New York City in 1943 to Rose (née Levine) and Max Lefkowitz. He reads a lot and is inspired by the family physician to study medicine.

Robert Lefkowitz and Marc Caron are developing [3H]dihydroalprenolol which enables the direct study of receptors. They collaborate with Rusty Williams and further create comparable assays for α-adrenergic receptors and a variety of tools such as photoaffinity probes, affinity chromatography matrices and computer based analysis for various adrenergic receptor subtypes.