Ada E. Yonath

Next Generation Environmental Friendly Antibiotics


Abstract

Resistance to antibiotics and the spread of antibiotics’ metabolites are severe problem in contemporary medicine. In addition to structures of complexes of eubacterial-ribosomes with antibiotics paralyzing them that illuminated common pathways in the modes of antibiotics inhibitions, synergism, differentiation and resistance, recent structures of ribosome from a multi-resistant pathogenic bacteria identified features that can account for species-specific diversity in infectious-diseases susceptibility. Careful analysis and comparisons to ribosomes from benign bacteria indicated novel paths for the design of environmental-friendly degradable, species-specific antibiotics, thus also preserving the microbiome.


Cite


Specify width: px

Share

Related Content

Cite


Specify width: px

Share